(Natural) polymersApplicationCharacterizationCustomer publicationsFractal dimensionMaterialNanoparticles & colloidsParticlesSAXSShapeSizeTechnique

Soft cellulose II nanospheres: sol–gel behaviour, swelling and material synthesis

Beaumont, Marco; Rosenfeldt, Sabine; Tardy, Blaise L.; Gusenbauer, Claudia; Khakalo, Alexey; Nonappa; Opietnik, Martina; Potthast, Antje; Rojas, Orlando J.; Rosenau, Thomas

High axial aspect crystalline nanomaterials have emerged as polymeric building blocks for the construction of supermaterials. In contrast to this form, amorphous nanospheres have remained largely untapped. This is especially peculiar in the context of material assembly, due to the wide range of opportunities they offer by virtue of their…
27 January 2020
ApplicationCharacterizationCustomer publicationsInorganic materialMaterialParticlesProteins & DNA/RNASAXSShapeSizeStructural biologyTechnique

Probing the Nanostructure and Arrangement of Bacterial Magnetosomes by Small-Angle X-Ray Scattering

Rosenfeldt, Sabine; Riese, Cornelius N.; Mickoleit, Frank; Schüler, Dirk; Schenk, Anna S.

Magnetosomes are membrane-enveloped single-domain ferromagnetic nanoparticles enabling the navigation of magnetotactic bacteria along magnetic field lines. Strict control over each step of biomineralization generates particles of high crystallinity, strong magnetization, and remarkable uniformity in size and shape, which is particularly interesting for many biomedical and biotechnological…
27 January 2020
ApplicationCharacterizationCustomer publicationsInorganic materialMaterialNanoparticles & colloidsParticle size and size distributionParticlesSAXSTechnique

Rapid synthesis of [Au25(Cys)18] nanoclusters via carbon monoxide in microfluidic liquid-liquid segmented flow system and their antimicrobial performance

Huang, He; Hwang, Gi Byoung; Wu, Gaowei; Karu, Kersti; Du Toit, Hendrik; Wu, Han; Callison, June; Parkin, Ivan P.; Gavriilidis, Asterios

Atomically precise thiolate-gold nanoclusters with well-defined structures attract attention for use in various applications. However, most of the recently reported synthetic methods rely on prolonged synthesis times (a few hours to days) in order to produce high purity materials with a single cluster size. Such extended synthesis times make these…
27 January 2020
(Natural) polymersApplicationCharacterizationCustomer publicationsMaterialNanoparticles & colloidsParticlesSAXSShapeSizeTechniqueTemperature

Investigation of the internal structure of thermoresponsive diblock poly(2-methyl-2-oxazoline)-b-poly[N-(2,2-difluoroethyl)acrylamide] copolymer nanoparticles

Babuka, David; Kolouchova, Kristyna; Hruby, Martin; Groborz, Ondrej; Tosner, Zdenek; Zhigunov, Alexander; Stepanek, Petr

The poly(2-methyl-2-oxazoline)-b-poly self-assembled nanoparticles show great potential in biological applications as, e.g., 19F MRI tumour diagnostic agents. As such their internal structure needs to be thoroughly investigated while the results also help to understand temperature-dependent self-assembly behaviour of copolymers comprised of the hydrophilic and…
27 January 2020
ApplicationCharacterizationCustomer publicationsInorganic materialMaterialNanoparticles & colloidsParticle size and size distributionParticlesSAXSTechnique

Single-step preparation of mono-dispersed sulfur nanoparticles for detention of copper

Shevchenko, Natalia; Steinhart, Milos; Tomšík, Elena

Application of sulfur nanoparticles results from biocompatibility, biodegradability, and non-toxicity of the shell that covers sulfur nanoparticles. However, to prepare uniform sulfur nanoparticles still remains a challenge; particularly in aqueous medium when the size of sulfur nanoparticles is not more than 20 nm. In the current work, the detailed investigation…
27 January 2020
ApplicationCharacterizationCustomer publicationsMaterialNanoparticles & colloidsParticle size and size distributionParticlesSAXSTechnique

A Cross-Method Comparison of Sub-10 nm Nanoparticle Size Distribution

Yang, Ye; Liao, Suiyang; Luo, Zhi; Qi, Runzhang; Mac Fhionnlaoich, Niamh; Stellacci, Francesco; Guldin, Stefan

Accurate nanoparticle (NP) size determination is essential across research domains, with many functions in nanoscience and biomedical research being size-dependent. Although transmission electron microscopy (TEM) is capable of resolving a single NP down to the sub-nm scale, the reliable representation of entire populations is plagued by challenges in providing statistical…
27 January 2020
ApplicationCharacterizationCustomer publicationsMaterialMetalsNanoparticles & colloidsOtherParticle size and size distributionParticlesSAXSTechniqueTemperature

An in situ SAXS investigation of the formation of silver nanoparticles and bimetallic silver–gold nanoparticles in controlled wet-chemical reduction synthesis

F. Garcia, Paulo R. A.; Prymak, Oleg; Grasmik, Viktoria; Pappert, Kevin; Wlysses, Wagner; Otubo, Larissa; Epple, Matthias; P. Oliveira, Cristiano L.

We present a study on the formation of silver (Ag) and bimetallic silver–gold (AgAu) nanoparticlesmonitored by in situ SAXS as well as by ex situ TEM, XRD and UV-vis analysis in a flow reactor at controlled reaction temperature. The formation mechanism of the nanoparticles is derived from the structural parameters…
27 January 2020
ApplicationCharacterizationCustomer publicationsGISAXSInorganic materialsMaterialMetalsOtherParticlesSurface structure and patternsTechnique

Ultrathin Homogenous AuNP Monolayers as Tunable Functional Substrates for Surface-Assisted Laser Desorption/Ionization of Small Biomolecules

Liu, Zhen; Zhang, Peng; Kister, Thomas; Kraus, Tobias; Volmer, Dietrich A.

A series of ultrathin, homogenous gold nanoparticle (AuNP) substrates for surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) were prepared using a simple air/water interface approach. These SALDI substrates enabled soft ionization and provided significant improvements in terms of signal intensities and reduced background levels in comparison to other AuNP morphologies for…
27 January 2020
(Natural) polymersApplicationCharacteristic dimensionCharacterizationCustomer publicationsMaterialNanoparticles & colloidsParticlesSAXSTechnique

Preparation and liquid crystal phase properties of discotic cellulose nanoparticles

Li, Chenxi; Evans, Julian; Wang, Nan; Guo, Tingbiao; He, Sailing

Understanding the behavior of fluids with inhomogeneous structural properties is critical for many industrial and biological materials. Sulfuric acid hydrolysis of cotton with ultrasonic treatment and low-speed centrifugation during purification yields “spiky” discotic cellulose particles. Amorphous cellulose remained in solution and forms discotic units which may be nucleated by crystalline…
27 January 2020
ApplicationCharacterizationCustomer publicationsLipidsMaterialParticle interactionsParticlesPhase analysisSAXSSizeStructural biologySurfactantsTechnique

Characterization of phospholipid vesicles containing lauric acid: physicochemical basis for process and product development

Farkuh, Laura; Hennies, Paulo T.; Nunes, Cláudia; Reis, Salette; Barreiros, Luisa; Segundo, Marcela A.; Oseliero Filho, Pedro L.; Oliveira, Cristiano L. P.; Cassago, Alexandre; Portugal, Rodrigo V.; Muramoto, Rodrigo A.; Carretero, Gustavo P. B.; Schreier, Shirley; Chaimovich, Hernan; Cuccovia, Iolanda M.

Lauric acid (LAH) strongly inhibits the growth of acne-causing bacteria. LAH is essentially water-insoluble and the solubility of laurate (LA) salts are medium and temperature dependent. Hence, LAH/LA preparations are difficult to formulate. Here we fully characterized phospholipid vesicles containing up to 50 mol% LAH. Vesicles of dipalmitoylphosphatidylcholine (DPPC) containing…
27 January 2020