News & events - Xenocs

ECIS 2023

3-8 September, 2023. Xenocs is pleased to attend the 37th conference of European Colloid & Interface Society from September 3-8 in Naples, Italy. Meet us at our booth!

[email protected]4 September 2023

News Type of articles

SAXS in the Pharmaceutical Industry

Short online course
4 & 5 October 2023 14:00–16:00 CEST

Register to our interactive two-day short course focused on the benefits and use of Small Angle X-ray Scattering (SAXS) for the pharmaceutical industry.

[email protected]21 August 2023

Events Type of articles

August 30 – September 1, 2023. Xenocs is pleased to attend the annual conference of the Italian Synchrotron Radiation Society (SILS) from Wednesday 30 August until Friday 1 September 2023 in Rome, Italy. Meet us at our booth!

[email protected]19 August 2023

News Type of articles

ECNP-2023

28-31 August, 2023. Xenocs is pleased to attend the 11th ECNP International Conference on Nanostructured Polymers and Nanocomposites from August 28-31 in Lodz, Poland. Meet us at our booth!

[email protected]16 August 2023

News Type of articles

IUCR 2023

22-29 August, 2023. Xenocs is pleased to attend the 26th Congress and General Assembly of the International Union of Crystallography from August 22-29, 2023 in Melbourne, Australia. Meet us at our booth!

[email protected]16 August 2023

News Type of articles

Xenocs Announces a New Partner in the Middle East

Xenocs is delighted to announce a new partnership with ProLab Systems, a leading laboratory solution provider in the Middle East. This company will represent Xenocs in this region. This partnership marks a significant expansion into the Middle East region.

[email protected]19 July 2023

News Type of articles

EBSA 2023

July 31 - August 4, 2023. Xenocs will attend the EBSA Congress 2023 from September 19-23 in Stockholm, Sweden. We will present a poster on "Small Angle X-ray Scattering (SAXS) as a Powerful Nano-Analytic Tool for Pharmaceutics". Let's discuss how SAXS can help your research projects!

[email protected]18 July 2023

News Type of articles

ICR 2023

July 29 - August 4, 2023. Xenocs is pleased to attend the 10th International Congress on Rheology from July 29 - August 4, 2023 in Athens, Greece. We will present a poster on "Investigating shear sensitive samples with laboratory SAXS". We will be pleased to welcome you to our booth…

[email protected]18 July 2023

News Type of articles

DXC 2023

7-11 August, 2023 Xenocs is pleased to attend the 2023 Denver X-ray Conference from August 7-11 in The Westin Chicago Lombard, Lombard, Illinois, USA. Meet us at our booth!

[email protected]17 July 2023

Application notes Application notes-Pharma News Type of articles

SAXS as a tool to study Lipid Nanoparticles

Lipid nanoparticles (LNPs) are one of the most exciting technologies in the drug delivery world. Previously used to study lipid nanoparticles and lipoplexes, small angle X-ray scattering (SAXS) has proven to be an excellent technique for characterizing the structure of LNPs.

Marie16 May 2023

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News Type of articles

SAXS in the Pharmaceutical Industry

Short online course
4 & 5 October 2023 14:00–16:00 CEST

Register to our interactive two-day short course focused on the benefits and use of Small Angle X-ray Scattering (SAXS) for the pharmaceutical industry.

[email protected]21 August 2023

News Type of articles

ECNP-2023

28-31 August, 2023. Xenocs is pleased to attend the 11th ECNP International Conference on Nanostructured Polymers and Nanocomposites from August 28-31 in Lodz, Poland. Meet us at our booth!

[email protected]16 August 2023

News Type of articles

DXC 2023

7-11 August, 2023 Xenocs is pleased to attend the 2023 Denver X-ray Conference from August 7-11 in The Westin Chicago Lombard, Lombard, Illinois, USA. Meet us at our booth!

[email protected]17 July 2023

Application notes Application notes-Pharma News Type of articles

SAXS as a tool to study Lipid Nanoparticles

Marie16 May 2023

News

UK Colloids 2023

17-19 July, 2023. Xenocs is pleased to attend the UK Colloids 2023 conference from July 17-19 in Liverpool, United Kingdom. Meet us at our booth!

[email protected]13 May 2023

News Type of articles

Xenocs Couette stage for shearSAXS – complement your rheological studies with nanostructural information

Learn more about this sample environment and its applications

[email protected]11 May 2023

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Events Type of articles

ECIS 2023

3-8 September, 2023. Xenocs is pleased to attend the 37th conference of European Colloid & Interface Society from September 3-8 in Naples, Italy. Meet us at our booth!

[email protected]4 September 2023

Events Type of articles

SILS 2023

[email protected]19 August 2023

Events

ACA-23

07-11 July, 2023. Xenocs is pleased to attend the 73rd ACA Annual Meeting from July 7-11, in Baltimore, USA. Come by booth 209 to learn about our comprehensive x-ray scattering instrument portfolio and what solutions we have for your research!

[email protected]5 May 2023

Events

64 Polish Crystallographic Meeting

6-7 July, 2023. We are pleased to attend the 64th Polish Crystallographic Meeting from July 6-7 in Wrocław, Poland. Meet us at our booth!

[email protected]3 May 2023

Events News

AOCS 2023

April 30- May 3, 2023. Xenocs is pleased to attend the 2023 AOCS Annual Meeting & Expo from April 30 - May 3 in Colorado Convention Center, Denver, Colorado, USA. Meet us at our booth!

[email protected]2 May 2023

Events News Webinar

Nanoscale characterization of lignocellulosic materials with laboratory SAXS/WAXS

Webinar

Presented by Dr. Paavo Penttilä from Aalto University, Finland.

[email protected]16 April 2023

Events News Type of articles

MRS Spring Meeting 2023

Xenocs is pleased to attend the MRS (Materials Research Society) Spring Meeting from April 10-14 in San Francisco, USA. Meet us at our booth!

[email protected]30 March 2023

Events News Type of articles

NSSM-2023

17-18 January, 2023. Xenocs is pleased to attend the Nordic Workshop on Scattering from Soft Matter (NSSM-2023) from January 17-18 at NTNU in Trondheim, Norway. Meet us at our booth!

[email protected]16 January 2023

Events Webinar

Laboratory SAXS as a tool to characterize complex self-assembly behaviours in aqueous solutions

Webinar

Presented by Dr Alessandra del Giudice from Sapienza University of Rome.

Marie2 December 2022

Events News Type of articles

2022 AIChE Annual Meeting

13 - 18 November 2022. Xenocs will attend the 2022 AIChE (American Institute of Chemical Engineers) Annual Meeting from 13 to 18 November 2022 in Phoenix, AZ, USA. Come and meet us at our booth #618 to discuss about our latest SAXS in the lab solutions.

Marie10 November 2022

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Model	Beam size at focus (µm)	Divergence (mrad)	Flux (ph/sec)	Typical application
GeniX 3D Cu High Flux *	< 190	6	> 400 x 10⁶	Protein crystallography Micro stress analysis Powder diffraction
GeniX 3D Mo High Flux	< 130	5	> 25 x 10⁶	Small Molecule crystallography High pressure
GeniX 3D Cr High Flux	< 190	6	> 300 x 10⁶	Stress Analysis
GeniX 3D Cu High Convergence *	60	70 x 35	> 400 x 10⁶	Rapid X-ray Reflectometry (full beam) Scanning x-ray reflectometry (with slit) Micro x-ray fluorescence Small spot diffraction on thin film
GeniX 3D Cu Low Convergence *	< 250	3	> 120 x 10⁶	Small Angle X-ray Scattering Protein Crystallography


Model	Beam size at focus (µm)	Divergence (mrad)	Flux (ph/sec)	Typical application
GeniX 3D Cr Micro Spot	< 30	17	> 12 x 10⁶	Stress Analysis Micro-XRF Micro-XRD
GeniX 3D Cu Micro Spot	< 30	17	> 18 x 10⁶	Stress Analysis Micro-XRF Micro-XRD
GeniX 3D Mo Micro Spot	< 55	10	> 1.8 x 10⁶	Micro-XRF Micro-XRD
GeniX 3D Cu High Convergence *	60	70 x 35	> 400 x 10⁶	Rapid X-ray Reflectometry (full beam) Scanning x-ray reflectometry (with slit) Micro x-ray fluorescence Small spot diffraction on thin film


Mirror type	Figure	Optic efficiency (calculated over mirror length for 70µm source)
Standard Montel mirrors		Eff = 42%
Xenocs FOX 3D mirrors		Eff = 62%


Model	Beam size at focus (mm) with 60 µm source	Divergence (mrad)	Typical application
FOX 3D Cu 14-39 (♦)	0.19 x 0.19	5.4	Protein crystallography (♦) Powder diffraction
FOX 3D Cu 12-53	0.3 x 0.3	3	Protein crystallography (Long Unit Cells) Powder diffraction
FOX 3D Mo 10-31	0.13 x 0.13	4	Small molecule crystallography High pressure diffraction
FOX 3D Ag 10-30	0.13 x 0.13	3	Small molecule crystallography High pressure diffraction
FOX 3D Cr 8-30	0.20 x 0.20	6	Protein crystallography (S-SAD) Stress analysis
FOX 1D Cu 12-53	0.3	3	XRD, Powder Diffraction


Model	Beam size at focus (mm) with 60 µm source	Divergence (mrad)	Typical application
FOX 2D Mo 25-25 (♦)	0.08 x 0.08	5	Small mollecule crystallography High pressure crystallography
FOX 2D Cu 25-25 (♦)	0.08 x 0.08	5.3	Protein crystallography (♦) Micro Diffraction, Reflectometry
FOX 3D Cu 21-21 HC (♦)	0.08 x 0.08	70 x 35	Rapid x-ray Reflectometry (full beam) Scanning x-ray Reflectometry (with slit) Micro-XRF
FOX 3D Cu 28-10	0.04 x 0.04	17	Stress Analysis, Micro-diffraction, Micro-XRF
FOX 3D Cr 30-8	0.04 x 0.04	17	Stress Analysis, Micro-diffraction, Micro-XRF


Element of interest	Reference
O, F, Na, Mg, Al, Si, P, S	XAN-1
Nitrogen	XAN-2
Carbon	XAN-3
Boron	XAN-4
Mg, Al , Si	XAN-5
Be	XAN-6


Model	Detailed specifications
Synchrotron scatterless slits (♦)	Please contact us for any technical information Discover what our customers say about it!
X-ray alignment camera (♦)	Please contact us for any technical information
Pin Diode detector (♦)	Please contact us for any technical information
Beam stop with integrated Pin Diode	Please contact us for any technical information



Source	Microfocus sealed tube: Cu, 30W/30µm, point focus. ( DIN EN 12543-5) MetalJet source D2+ (Ga). Motorized Dual source or triple source (Cu/Mo/Cr/Ga).
Optics	Patented 2D single reflection multilayer optics.
Detector	In-vacuum motorized 3-axis detectors for 2D SAXS/WAXS (Q-Xoom): --Pilatus3 R 300K hybrid photon counting detector --Eiger2 R (1M, 4M) hybrid photon counting detectors Optional WAXS detectors for SWAXS: --Pilatus3 R 100K hybrid photon counting detector --Motorized 3-axis Eiger2 R 500K hybrid photon counting detector
Sample chamber	Large vacuum chamber. On-axis sample viewing (parallax free). Attachments for operation of sample in air.
Key features	Clean Beam technology: high flux and low background beamline. Beamstopless measurement: SAXS acquisition continuously without any beamstop. Q-Xoom: Automatic change of measurement configuration over all instrument Q-range with no movement of sample measuring position. Virtual detector mode: surfaces of detection > 200 mm² x 200 mm².
Measurement capability	Nanoparticles size up to 300 nm, 500 nm or 900 nm in diameter depending on Xeuss model. Nanoparticles size up to > 2.5 microns with optional motorized Bonse-Hart module for automatic sequential USAXS/SAXS/WAXS measurements. Scattering measurements up to 2Ɵ>70° with Q-Xoom. Qmax > 49 nm^-1
Sample environment	Standard holders (multi-samples): solids, capillaries, powders. Sample holders for powders and gels. Flowcells for liquids: --- Low noise flowcell --- Capillary flowcell --- Automatic Sample Changer --- BioCube measuring cell with dynamic monitoring (compatible with pipetting robot) Temperature stages: --- Multi-purpose X-Ray Temperature Stage (-30°C to 150°C) --- High temperature sample stage (-150°C to 350°C) --- Extended high temperature sample stage (amb - 1000°C) Tensile Stage (00-600N). Humidity stage (10%-90% from ambient to 60°C). Shear stage Temperature compatible GiSAXS stage Other sample stages available under request
Software	Acquisition software with automatic data reduction in absolute units and live data display. XSACT (X-ray Scattering Analysis and Calculation Tool) for data analysis and interpretation.
General parameters	Models & Footprint : Xeuss 3.0 C (1 m x 3 m), HR (1 m x 5 m), UHR (1 m x 8 m). Maximum power consumption: < 3000 W (single phase power)


BioXolver configurations	BioXolver	BioXolver L
Utilisation	Research on biological macro-molecules in solution	Research on biological macro-molecules, including large complexes and interactions
X-ray source	Microfocus GeniX 3D, MetalJet, add-on to RAG	0.02-0.3nm
Optic	Aspheric single reflection multilayer optic
Collimation	Motorized scatterless point collimation	variable
Sample cell	Xenocs thermalized BioCube flow-cell with camera and pump
Sample handling	Pipetting robot with disposable tips
Sample capacity	Up to 2 x 96 well plates (thermalized)
Minimum sample volume	Down to 5 μL
Cleaning	Automated cleaning and drying with three cleaning fluids
Detector	Dectris in-vacuum hybrid pixel photon counting detector
Detector configuration	Fixed detector distance	Variable detector distance
Data reduction and analysis software	RAW and ATSAS
Q-range and typical protein size*	0.006 Å-1 / MW < 200 MDa / Rg < 135 Å	0.003 Å-1 / MW < 1.5 GDa / Rg < 270 Å
Overall length	3.2 m (2.7 m as add-on to existing source)	4.2 m
Options	UV-Vis, separate temperature control for sample trays and BioCube	UV-Vis, separate temperature control for sample trays and BioCube
Services	Installation, training, hot-line, maintenance contract	Installation, training, hot-line, maintenance contract



Source and optics	Microfocus sealed tube: Cu, 30W/30µm, point focus. ( DIN EN 12543-5) Patented 2D single reflection multilayer optics.
Detector	Dectris Pilatus 3 hybrid photon counting detectors. Two fixed detectors for continuously and simultaneously. SAXS and WAXS acquisition up to 2θ=60°.
Beam Path	Windowless beam path entirely under vacuum from beam delivery system to detector sensor
Key features	Clean Beam technology: high flux and low background beamline. Beamstopless measurement: SAXS acquisition continuously without any beamstop. Virtual detector mode: > 200° azimuth coverage with rotation of sample.
Measurement capability	Nanoparticles size up to 250 nm in diameter.
Sample environment	Standard holders: solids, capillaries, powders. Sample holders for powders and gels. Flow cells for liquids: --- Low noise flow cell --- Capillary flow cell Automatic Sample Changer Temperature stages: --- Multi-purpose X-Ray Temperature Stage (-20°C to 150°C) --- High temperature sample stage (-150°C to 350°C) --- Extended high temperature sample stage (amb - 700°C) Tensile Stage (0-200N). GiSAXS stage compatible with high temperature sample stage. Custom stages on request.
Software	Acquisition software with automatic data reduction in absolute units and live data display. XSACT (X-ray Scattering Analysis and Calculation Tool) for data analysis and interpretation.
General parameters	Fooprint: < 1x1 m². Weight: ~ 520 kg. Maximum power consumption: < 2000 W (single phase power). Self-contained: no external fluids required.
Warranty	Two years warranty and three years on X ray source.

Useful links

X-ray beam delivery system

The combination of an innovative design and the FOX3D single reflection optics makes the GeniX3D a unique solution on the market.

High flux solutions

Small spot solutions

X-ray Optics

Xenocs proposes a wide range of optics for both XRD and XRF applications.

2D-3D Beam shaping X-ray Optics

High Flux Optics

Small Spot Optics

Collimating Optics

1D Beam shaping X-ray Optics

High Flux Optics

Collimating Optics

XRF Optics

X-ray beam accessories

In addition to our high quality optical components and beam delivery systems, we propose accessories to optimize the performance of your setup.

Xeuss 3.0 specifications

Plenty of space for sample environment

With its large chamber and concept ensuring stationary sample during measurement, the Xeuss 3.0 is the perfect X-ray scattering platform instrument for now and the future.

Ultimate performance

The Xeuss 3.0 offers a maximum flexibility of measurement configurations to get the best possible data quality on any type of sample.

Xeuss 3.0 shown with Q-Xoom transparency to illustrate the moving detector.

Maximum flexibility

Provide structural tools to a large community of users with full remote operation capability and access to a unique range of length-scales.

Q-Xoom – enjoy the flexibility of full-range computer-controlled detector travel

Measure probe lengths as large as 4.5 microns together with nanoscale information

Optimize your experiment to any type of sample (absorption, fluorescence, characteristic dimensions)

Simultaneously from atomic to nanoscale

No need to repeat SAXS and WAXS measurement, you get two measurements within one exposure.

Extensive and powerful suite of data analysis algorithms

XSACT includes an extensive array of analysis modules for sample characterization of size, structure and texture of multiple types of materials including nanoparticles and polymers.

Low cost of ownership

Get nanoscale information on a day to day basis to improve your material process or validate your research models.

Accurate and high dynamic range measurement

Focus your attention on science and data interpretation, you can rely on your data.

Publication quality figure presentation

XSACT is a time saver as it bundles all the tools to create publication-ready figures without the need for another visualization software.

High quality SAXS data in the lab

Measurements previously only possible at synchrotron facilities can now be done in the lab.

High throughput measurements and results

Full automation from sample to final results on up to 192 samples.

In-line SEC and UV-Vis combined with SAXS – also in the lab!

Obtain the structure of small and large protein species through in-line gel filtration

BioXolver specifications

*Theoretical limit assuming globular proteins

智能工作流程和用户体验

使用XSACT可使用户用最小投入获得数据解析结果。

样品 – 测试 – 分析 – 报告 – 节约时间

智能工作流程和用户体验

使用XSACT可使用户用最小投入获得数据解析结果。

样品 – 测试 – 分析 – 报告 – 节约时间

在实验室中得到高质量SAXS数据

以前的测试只能在同步辐射完成，现在也可在实验室中实现。

SAXS可以和在线SEC、UV-Vis联用 – 在实验室也可以实现!

通过内置胶体过滤获取不同尺寸蛋白质种类的结构

低样品消耗量

低至5μL。目前是市场上最低的样品消耗量。

内容广泛、性能强大的数据分析算法软件

XSACT包括一系列的广泛的分析模块，用于对多种类型的材料包括纳米颗粒和聚合物的尺寸、结构和织构进行样品表征等。

同时从原子级别到纳米尺寸

无需重复SAXS和WAXS测试，您可以在一次曝光内同时得到所有测量结果。

高精度高动态范围测量

获取可信赖的数据，将您的注意力集中在科学和数据解释上。

更高的灵活性

为广大用户群体提供全远程自动操作的、具备表征超大纳米尺度范围的独特工具。

Q-Xoom–享受全范围计算机控制探测器行程的灵活性

测量尺度可达4.5微米，并获取纳米尺度信息