ApplicationCharacterizationCosmetics & consumer careCustomer publicationsLiquid crystalsMaterialPhase analysisSAXSSurfactantsTechnique

The structure of spray-dried detergent powders

Farshchi, Amin; Hassanpour, Ali; Bayly, Andrew E.

The complex multiscale structure of spray dried detergent granules has been characterized using a complementary range of techniques including scanning electron microscopy (SEM), image analysis, wide angle and small angle X-ray scattering (WAXS, SAXS) and X-ray microtomography. A complex composite structure is revealed due to the multiphase nature of the…
ApplicationCharacterizationCustomer publicationsMaterialSAXSSelf-assembled materialShapeSizeStructural biologySurfactantsTechniqueTemperature

Self-Assembly of the Bio-Surfactant Aescin in Solution: A Small-Angle X-ray Scattering and Fluorescence Study

Dargel, Carina; Geisler, Ramsia; Hannappel, Yvonne; Kemker, Isabell; Sewald, Norbert; Hellweg, Thomas

This work investigates the temperature-dependent micelle formation as well as the micellar structure of the saponin aescin. The critical micelle concentration ( cmc ) of aescin is determined from the concentration-dependent autofluorescence (AF) of aescin. Values between cmcaescin,AF (10°C) = 0.38 ± 0.09 mM and cmcaescin,AF (50°C) = 0.32 ±…
(Hydro)gelsApplicationCharacterizationCustomer publicationsMaterialSAXSShapeSizeStructural biologySurfactantsTechnique

Deoxycholic acid and l-Phenylalanine enrich their hydrogel properties when combined in a zwitterionic derivative

Travaglini, Leana; di Gregorio, Maria Chiara; Severoni, Emilia; D’Annibale, Andrea; Sennato, Simona; Tardani, Franco; Giustini, Mauro; Gubitosi, Marta; Del Giudice, Alessandra; Galantini, Luciano

Hypothesis Sodium Deoxycholate (NaDC) and Phenylalanine (Phe) are important biological hydrogelators. NaDC hydrogels form by lowering the pH or by increasing the ionic strength. Phe gels form from saturated solution by thermal induction and slow kinetics. The resulting gels hold great potential in medicine and biology as drug carriers and…
(Natural) polymersApplicationCharacterizationCustomer publicationsMaterialSAXSShapeSizeStructural biologySurfactantsTechnique

Block copolymers as bile salt sequestrants: intriguing structures formed in a mixture of an oppositely charged amphiphilic block copolymer and bile salt

Schillén, Karin; Galantini, Luciano; Du, Guanqun; Del Giudice, Alessandra; Alfredsson, Viveka; Carnerup, Anna M.; Pavel, Nicolae V.; Masci, Giancarlo; Nyström, Bo

To study the formation and characterize the structure of mixed complexes of oppositely charged block copolymers and surfactants are of great significance for practical applications, e.g., in drug carrier formulations that are based on electrostatically assisted assembly. In this context, biocompatible block copolymers and biosurfactants (like bile salts) are particularly…
ApplicationCharacterizationCustomer publicationsMaterialSAXSSizeStructural biologySurfactantsTechnique

Dynamics of proteins confined in non-ionic bicontinuous microemulsions: a FCS study

Wrede, Oliver; Großkopf, Sören; Seidel, Thorsten; Hellweg, Thomas

In our present work we present an approach which allows one to confine proteins in structurally nearly identical bicontinuous microemulsions with systematically decreasing water domain size. It is shown that sub-diffusive behaviour occurs already at water domain sizes below 13 nm. However, above 13 nm normal diffusion is seen. Moreover,…
(Natural) polymersApplicationCharacteristic dimensionCharacterizationCompositesCustomer publicationsGISAXSGIWAXSInorganic materialMaterialPhase analysisPorous materialRenewable energySAXSSelf-assembled materialSurfactantsTechniqueTemperatureThin filmsWAXS

Ordered Mesoporous to Macroporous Oxides with Tunable Isomorphic Architectures: Solution Criteria for Persistent Micelle Templates

Lokupitiya, Hasala N.; Jones, Alexis; Reid, Barry; Guldin, Stefan; Stefik, Morgan

Porous and nanoscale architectures of inorganic materials have become crucial for a range of energy and catalysis applications, where the ability to control the morphology largely determines the transport characteristics and device performance. Despite the availability of a range of block copolymer self-assembly methods, the conditions for tuning the key…
12 March 2019
ApplicationCharacteristic dimensionCharacterizationCustomer publicationsLiquid crystalsMaterialOtherPhase analysisSAXSSurfactantsTechnique

Liquid crystal phantom for validation of microscopic diffusion anisotropy measurements on clinical MRI systems

Nilsson, Markus; Larsson, Johan; Lundberg, Dan; Szczepankiewicz, Filip; Witzel, Thomas; Westin, Carl-Fredrik; Bryskhe, Karin; Topgaard, Daniel

Purpose To develop a phantom for validating MRI pulse sequences and data processing methods to quantify microscopic diffusion anisotropy in the human brain. Methods Using a liquid crystal consisting of water, detergent, and hydrocarbon, we designed a 0.5-L spherical phantom showing the theoretically highest possible degree of microscopic anisotropy. Data…
12 March 2019