Small molecule Crystallography refers to the X-ray diffraction analysis of molecules with very small unit cells (< 50 Angströms). The technique achieves fast and accurate molecular structure, at near atomic resolution, and enables the detection of molecular interactions that are essential in different applications such as biotechnology or chemistry.

Compared to macromolecular crystallography, small molecule analysis requires a shorter wavelength radiation in order to achieve this resolution. Typically Mo Kα (17,5 KeV), which has a lower efficiency, is used making the choice of the optical component even more critical.

Due to its unique single reflection design, FOX2D optics achieve higher intensity and efficiency for small crystal analysis as compared to traditional solutions (graphite, KB mirrors…).